Breast Cancer Incidence 2008
According to recent estimates by the U.S. government, ovarian cancer is the eighth most common cancer, with an estimated 21,650 new cases in 2008, but is the fifth most deadly, with an estimated 15,520 deaths in 2008. The fact that there is a genetic health – Relationship of ovarian cancer has been established beyond doubt. This is supported by the fact that there is an increased incidence of cancer among women with a family history of ovarian cancer. Studies of families have demonstrated the existence of ovarian cancer predisposition. Studies have also led to the identification of several genes as the cause of hereditary cancer risk in the family.
Reproductive, demographic and lifestyle factors influence the risk of developing ovarian cancer, but the major risk factor for ovarian cancer is a positive family history of disease. This makes the genetic link of ovarian cancer health even stronger. Studies have shown who have a threefold increased risk of developing ovarian cancer if you have a first – degree relative has had. Ovarian cancer has been clinically considered a component of cancer syndromes that are more strongly associated with ovarian cancer are BRCA1 or BRCA2 gene mutations.
There are some features family who have been members of the predisposing to an increased risk of developing ovarian cancer. These features show the link between genetic health ovarian cancer. If a person has a familial predisposition to ovarian cancer, which develop at a much earlier age than in cases where no history exists.She Positive family would also be prone to develop two or more primary cancers. For example, a person with a positive family history of ovarian cancer also may have breast cancer in their lifetime. Women also are likely predisposed to develop other types of cancer and benign features times.
Let us now turn to some other factors also affect the genetic link to ovarian cancer health. Age is one of the most important factors that one must regard. The incidence of ovarian cancer increases 30 to 50 years. After the incresed risk, but not at the same pace. The chances of developing cancer ovary before the age of thirty years is much lower even in families with a genetic predisposition. Another important factor to consider is the number of children a woman been given. With no children at all is associtated with an increased risk of ovarian cancer. This also applies to those who have a genetic predisposition to this cancer.
For women who take fertility drugs and still without children, the risk of ovarian cancer is high. There is also evidence that shows that hormone replacement therapy after menopause is associated with an increased risk of ovarian cancer. Surgeries such as hysterectomy is associated with lower risk ovarian cancer. This is true even for those with a positive family history. Use of oral contraceptives for 4 years or more is associated with an approximately 50% reduction in risk of ovarian cancer in the general population.
